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m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although they could play crucial roles in environmental adaptation. N 6-methyl-adenosine (m 6 A) is the most prevalent mRNA modification, established by "writer" and "eraser" proteins. It influences the clockwork in several taxa ...

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m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although they could play crucial roles in environmental adaptation. N6-methyl-adenosine (m6A) is the most prevalent

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(PDF) m6A RNA Methylation in Marine Plants: First Insights

2020-10-12  PDF Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional...

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m6A RNA Methylation in Marine Plants: First Insights

Globally, our results indicate that m6A RNA methylation could widely contribute to circadian regulation in seagrasses, potentially a ecting the photo-biological behaviour of these plants.

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(PDF) m6A RNA Methylation in Marine Plants: First Insights

Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although

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m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  Europe PMC is an archive of life sciences journal literature.

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m 6 A RNA Methylation in Marine Plants: First Insights and

Post-transcriptional RNA... DOAJ is a community-curated online directory that indexes and provides access to high quality, open access, peer-reviewed journals. ... m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms Miriam Ruocco, Luca Ambrosino, Marlene Jahnke, Maria Luisa Chiusano, Isabel ...

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m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  Mimulus sRNAs Are Wound Responsive and Associated with Transgenerationally Plastic Genes but Rarely Both

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m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  It influences the clockwork in several taxa, but only few studies have been conducted in plants and none in marine plants. Here, we provided a first inventory of m6A-related genes in seagrasses and investigated daily changes in the global RNA methylation and transcript levels of writers and erasers in Cymodocea nodosa and Zostera marina.

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m 6 A RNA methylation: from mechanisms to therapeutic

2021-2-1  The importance of m 6 A methylation as a mode of post-transcriptional gene expression regulation is evident in the crucial roles m 6 A-mediated gene regulation plays in numerous physiological and pathophysiological processes. Here, we review current knowledge on the mechanisms by which m 6 A exerts its functions and discuss recent advances that ...

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[PDF] m6A RNA Methylation in Marine Plants: First Insights

Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although they could play crucial roles in environmental adaptation. N6-methyl-adenosine (m6A) is the most prevalent mRNA

Inquire now

m6A RNA Methylation in Marine Plants: First Insights

Globally, our results indicate that m6A RNA methylation could widely contribute to circadian regulation in seagrasses, potentially a ecting the photo-biological behaviour of these plants.

Inquire now

(PDF) m6A RNA Methylation in Marine Plants: First Insights

Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although

Inquire now

m 6 A RNA Methylation in Marine Plants: First Insights and

2020-10-12  It influences the clockwork in several taxa, but only few studies have been conducted in plants and none in marine plants. Here, we provided a first inventory of m6A-related genes in seagrasses and investigated daily changes in the global RNA methylation and transcript levels of writers and erasers in Cymodocea nodosa and Zostera marina.

Inquire now

Holdings: m 6 A RNA Methylation in Marine Plants: First

m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms . Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles.

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m 6 A RNA methylation: from mechanisms to therapeutic

2021-2-1  The importance of m 6 A methylation as a mode of post-transcriptional gene expression regulation is evident in the crucial roles m 6 A-mediated gene regulation plays in numerous physiological and pathophysiological processes. Here, we review current knowledge on the mechanisms by which m 6 A exerts its functions and discuss recent advances that ...

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m 6 A RNA methylation regulates the fate of endogenous

By monitoring chromatin states and mRNA stability upon METTL3-METTL14 double depletion, we found that m 6 A methylation mainly acts by reducing the half-life of IAP mRNA, and this occurs by the recruitment of the YTHDF family of m 6 A reader proteins 5. Together, our results indicate that RNA methylation provides a protective effect in ...

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m 6 A RNA Methylation in Cardiovascular Diseases - PubMed

2020-10-7  Recent advances in knowledge about epigenetic mechanisms, especially RNA methylation, have revealed a close relationship between epigenetic modifications and CVDs and have brought to potential novel targets for diagnosis and treatment. ... Here, we provide a review of recent studies exploring RNA N 6-methyladenosine (m 6 A) modification, with ...

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Multiple functions of m 6 A RNA methylation in cancer

2018-3-27  First identified in 1974, m 6 A RNA methylation, which serves as a predominant internal modification of RNA in higher eukaryotes, has gained prodigious interest in recent years. Modifications of m 6 A are dynamic and reversible in mammalian cells, which have been proposed as another layer of epigenetic regulation similar to DNA and histone modifications. m 6 A RNA

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Gene expression regulation mediated through

2014-3-25  The methylation is dynamic and seems to have regulatory roles. The YTHDF domain family proteins preferentially bind to m 6 A in mRNA. The recognition of m 6 A in mRNA and other polyadenylated RNA ...

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m 6 A RNA methylation: from mechanisms to therapeutic

2021-1-20  Introduction. m 6 A is a chemical derivative of adenosine in RNA that plays important, wide-ranging roles in the regulation of gene expression. m 6 A modification of RNA occurs in most eukaryotes and is the most prevalent internal mRNA modification in mammals, where it is present at tens of thousands of sites across the transcriptome, at a frequency of 0.15–0.6% of all

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m 6 A RNA Methylation Controls Neural Development and

2018-6-16  m 6 A is the most abundant modification in eukaryotic mRNAs, which accounts for more than 80% of RNA base methylations, and exists in various species [3,4,5,6,7,8,9]. m 6 A modification draws significant attention after nuclear RNA m 6 A was reported to be one of the major substrates for FTO, which was identified as a demethylase that regulates m 6 A

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m6A RNA methylation promotes XIST-mediated

2016-9-7  These proteins bind and recruit the m 6 A-methylation complex to specific sites within XIST, leading to m 6 A formation at adjacent sites. Furthermore, we show that m 6 A in XIST recruits the m 6 ...

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Natural Variation in RNA m6A Methylation and Its

Abstract. N 6-methyladenosine (m 6 A) is the most abundant modification of eukaryotic mRNA. Although m 6 A has been demonstrated to affect almost all aspects of RNA metabolism, its global contribution to the post-transcriptional balancing of translational efficiency remains elusive in plants. In this study, we performed a parallel analysis of the transcriptome-wide mRNA m 6 A

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Novel insights on m 6 A RNA methylation in

2018-7-21  N6-methyladenosine (m 6 A), the most prevalent modification of mammalian RNA, has received increasing attention. Although m 6 A has been shown to be associated with biological activities, such as spermatogenesis modulation, cell spermatogenesis and pluripotency, Drosophila sex determination, and the control of T cell homeostasis and response to heat

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The role of m 6 A RNA methylation in human cancer

2019-5-29  Acumulating evidence shows that, m 6 A RNA methylation has an outsize effect on RNA production/metabolism and participates in the pathogenesis of multiple diseases including cancers. Until now, the molecular mechanisms underlying m 6 A RNA methylation in various tumors have not been comprehensively clarified. In this review, we mainly summarize ...

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Gene expression regulation mediated through

2014-3-25  The methylation is dynamic and seems to have regulatory roles. The YTHDF domain family proteins preferentially bind to m 6 A in mRNA. The recognition of m 6 A in mRNA and other polyadenylated RNA ...

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The dynamics of N 6 -methyladenine RNA modification in

2021-6-24  N 6-methyladenine (m 6 A) RNA methylation is one of the most common RNA modifications in prokaryotes and eukaryotes []. m 6 A methylation and its biological functions in prokaryotes and eukaryotes have been the focus of research, recently [2,3,4,5,6].Modification of m 6 A methylation was first reported 40 years ago [7, 8].The modification contributes to the

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Analysis of Nucleic Acids Methylation in Plants SpringerLink

2017-4-29  Methylation modifications, notably in the forms of 5-methylcytosine (5-mC) and N 6-methyladenosine (m 6 A) in both DNA and RNA, perform important regulatory functions in various biological processes (Chen et al. 2016; Shen et al. 2014; Wu and Zhang 2014).DNA and RNA methylation occurs in almost all living organisms, from bacteria to fungi, plants, and mammals

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Dynamics and function of DNA methylation in plants

2018-5-21  Abstract. DNA methylation is a conserved epigenetic modification that is important for gene regulation and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental ...

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